2011-10-21 · DEHP which is an abbreviation for di(2-ethylhexyl) phthalate is a manufactured chemical that is commonly added to plastics to make them flexible. Other names for this compound are dioctyl phthalate (DOP) and bis(2-ethylhexyl) phthalate (BEHP). (Note that di-n-octyl phthalate however is the name for a different chemical.) Trade names used for DEHP include Platinol DOP Octoil Silicol 150 Bisoflex 81 and Eviplast 80. DEHP is a colorless liquid with almost no odor. It does not evaporate easily and little will be present in the air even near sources of production. It dissolves more easily in materials such as gasoline paint removers and oils than it does in water. It is present in many plastics especially vinyl materials which may contain up to 40 DEHP although lower levels are common. DEHP
2 days ago · Health risks posed by use of Di-2-ethylhexyl phthalate (DEHP) in PVC medical devices a critical review. Am J Ind Med 39(1) 100-11. 41 National toxicology programm the US department of health and human services (11/2006) Center for the evaluation of risks to human reproduction NTP-CERHR Monograph on the Potential Human Reproductive and
Di (2-ethylhexyl) phthalate (DEHP) is a widely used plastic additive. As an environmental endocrine disruptor it has been shown to be harmful to the mammalian reproductive system. Previous studies indicated that DEHP inhibited the development of mouse ovarian follicles.
2 days ago · DEHP is on the Proposition 65 list because it can cause cancer and birth defects or other reproductive harm. Exposure to DEHP may increase the risk of cancer and may also harm the male reproductive system. Exposure to DEHP during pregnancy may affect the development of the child. Proposition 65 requires businesses to determine if they must provide a warning about exposure to
What is DEHP DEHP which is an abbreviation for di(2-ethylhexyl) phthalate is a manufactured chemical that is commonly added to plastics to make them flexible. Other names for this compound are dioctyl phthalate (DOP) and bis(2-ethylhexyl) phthalate (BEHP). (Note that di-n-octyl phthalate however is the name for a different chemical.)
2021-7-13 · Bis (2-ethylhexyl) phthalate also known as di (2-ethylhexyl) phthalate or DEHP a branched-chain dioctyl ester of phthalic acid is the most important phthalate plasticizer used in Canada. In 1991 production of bis (2-ethylhexyl) phthalate in Canada totalled approximately 5 kilotonnes (kt) and an additional 5 kt were imported.
2020-9-3 · Allergic rhinitis (AR) is a common chronic inflammatory disease of the upper respiratory tract. Di (2-ethylhexyl) phthalate (DEHP) is a widely used plasticizer and belongs to environmental
Assay of vtg ERs and PPARs as endpoint for the rapid in vitro screening of the harmful effect of Di-(2-ethylhexyl)-phthalate (DEHP) and phthalic acid (PA) in zebrafish primary hepatocyte cultures. Maradonna F(1) Evangelisti M Gioacchini G Migliarini B Olivotto I Carnevali O.
Assay of vtg ERs and PPARs as endpoint for the rapid in vitro screening of the harmful effect of Di-(2-ethylhexyl)-phthalate (DEHP) and phthalic acid (PA) in zebrafish primary hepatocyte cultures. Maradonna F(1) Evangelisti M Gioacchini G Migliarini B Olivotto I Carnevali O.
2018-10-24 · Reduction of Di-2 ethylhexyl Phthalate (DEHP) in Respiratory Therapy Products . exposure to harmful chemicals that are known to pose health risks. DEHP is used as a plasticizer to make tubing and other medical plastics more flexible and is known to leach from plastic during use and thereby enter the patient. Respiratory therapy
The revised Drinking Water Directive aims to protect citizens and the environment from the harmful effects of contaminated drinking water and to improve access to drinking water. bis_2-ethylhexyl_phthalate_dehp_en.i5z. Support document outcome_msc_agreement_seeking_DEHP.zip. support_document_dehp_en.pdf. svhc_supdoc_dehp_publication_en.pdf
2019-8-1 · As one of the most common PAEs di-2-ethylhexyl phthalate (DEHP) has been shown by toxicological studies to be an endocrine disruptor that may cause cancer in humans and is listed as a priority contaminant by the US Environmental Protection Agency (USEPA) (Martino-Andrade and Chahoud 2010 Gao et al. 2016a Chen et al. 2018).
California ResidentsProposition 65. WARNING This product can expose you to chemicals including Di (2-ethylhexyl) phthalate (DEHP) which is known to the state of California to cause cancer and birth defects or other reproductive harm. For more information go to P65WArnings.ca.gov.
2015-7-26 · The study objective was to determine if the healthy participants were exposed to diethyl phthalate (DEP) and di (2-ethylhexyl) phthalate (DEHP) and if this exposure could be linked to the development of metabolic syndrome. The study included 103 healthy volunteers of similar age with normal BMI values waist circumference total cholesterol HDL LDL and triglycerides.
Phthalate esters are known to exert harmful effects on mammalian reproduction and fertility but their potential adverse effects on the hormonal functions of the ovary have not yet been elucidated in detail. Here we investigated the effects of di-(2-ethylhexyl) phthalate (DEHP) on the hypothalamic-pituitary-gonadal axis of young developing rats as well as on ex vivo steroidogenesis by
2011-10-6 · Approximately 55 of ingested DEHP is absorbed. DEHP is poorly absorbed through the skin. There are no quantitative absorption data for the inhalation route. Following ingestion DEHP is rapidly broken down in the gut to mono(2-ethylhexyl)phthalate and 2-ethylhexanol. 3 DEHP is lipophilic and tends to accumulate in adipose tissues.
The revised Drinking Water Directive aims to protect citizens and the environment from the harmful effects of contaminated drinking water and to improve access to drinking water. bis_2-ethylhexyl_phthalate_dehp_en.i5z. Support document outcome_msc_agreement_seeking_DEHP.zip. support_document_dehp_en.pdf. svhc_supdoc_dehp_publication_en.pdf
2016-10-7 · Di(2-ethylhexyl) phthalate (DEHP) is the most common plasticizer of polyvinyl chloride (PVC) products (Guo and Kannan 2011).Approximately 3–4 millions of tons of DEHP are produced each year worldwide and have been used in numerous consumer products commodities building materials and medical products (Heudorf et al. 2007).Since DEHP is not permanently bound to the PVC polymer in
Assay of vtg ERs and PPARs as endpoint for the rapid in vitro screening of the harmful effect of Di-(2-ethylhexyl)-phthalate (DEHP) and phthalic acid (PA) in zebrafish primary hepatocyte cultures. Maradonna F(1) Evangelisti M Gioacchini G Migliarini B Olivotto I Carnevali O.
2015-7-26 · The study objective was to determine if the healthy participants were exposed to diethyl phthalate (DEP) and di (2-ethylhexyl) phthalate (DEHP) and if this exposure could be linked to the development of metabolic syndrome. The study included 103 healthy volunteers of similar age with normal BMI values waist circumference total cholesterol HDL LDL and triglycerides.
2019-1-18 · phthalates DEHP DBP DiBP and BBP as toxic to reproductive health for example. In ani-mal trials Di(2-propylheptyl) phthalate (DPHP) has a harmful effect on the pituitary gland (hypophysis) and on the vital endocrine hormone the thyroid. The pituitary gland controls important bodily functions and the hormonal system of the body.
2016-10-7 · Di(2-ethylhexyl) phthalate (DEHP) is the most common plasticizer of polyvinyl chloride (PVC) products (Guo and Kannan 2011).Approximately 3–4 millions of tons of DEHP are produced each year worldwide and have been used in numerous consumer products commodities building materials and medical products (Heudorf et al. 2007).Since DEHP is not permanently bound to the PVC polymer in
2003-5-15 · The efficiency of two lypolytic enzymes (fungal cutinase yeast esterase) in the degradation of di-(2-ethylhexyl)-phthalate (DEHP) was investigated. The DEHP-degradation rate of fungal cutinase was surprisingly high i.e. almost 70 of the initial DEHP (500 mg/l) was decomposed within 2.5 h and nearly 50 of the degraded DEHP disappeared within the initial 15 min.
2021-6-12 · Five of the most widely used phthalates are di- (2-ethylhexyl) phthalate (DEHP) dibutyl phthalate (DBP) di-isononyl phthalate (DINP) di-isodecyl phthalate (DIDP) and benzyl butyl phthalate (BBP). These phthalates have been assessed within an EU program on Risk Assessment for new and existing chemical substances.
2013-12-5 · Di-2-ethylhexyl phthalate (DEHP) is a reproductive and developmental toxicant and the developing male reproductive tract is most sensitive to DEHP exposures. Because DEHP is used in many consumer products and is a ubiquitous environmental contami-nant humans are exposed to DEHP at some level on a daily basis throughout life from conception
Assay of vtg ERs and PPARs as endpoint for the rapid in vitro screening of the harmful effect of Di-(2-ethylhexyl)-phthalate (DEHP) and phthalic acid (PA) in zebrafish primary hepatocyte cultures. Maradonna F(1) Evangelisti M Gioacchini G Migliarini B Olivotto I Carnevali O.
2 days ago · Health risks posed by use of Di-2-ethylhexyl phthalate (DEHP) in PVC medical devices a critical review. Am J Ind Med 39(1) 100-11. 41 National toxicology programm the US department of health and human services (11/2006) Center for the evaluation of risks to human reproduction NTP-CERHR Monograph on the Potential Human Reproductive and
2018-2-22 · Di-2-ethylhexyl phthalate (DEHP) is extensively used as a plasticizer in many products especially medical devices furniture materials cosmetics and personal care products. DEHP is noncovalently bound to plastics and therefore it will leach out of these products after repeated use heating and/or cleaning of the products.
2021-6-12 · Five of the most widely used phthalates are di- (2-ethylhexyl) phthalate (DEHP) dibutyl phthalate (DBP) di-isononyl phthalate (DINP) di-isodecyl phthalate (DIDP) and benzyl butyl phthalate (BBP). These phthalates have been assessed within an EU program on Risk Assessment for new and existing chemical substances.
2016-10-7 · Di(2-ethylhexyl) phthalate (DEHP) is the most common plasticizer of polyvinyl chloride (PVC) products (Guo and Kannan 2011).Approximately 3–4 millions of tons of DEHP are produced each year worldwide and have been used in numerous consumer products commodities building materials and medical products (Heudorf et al. 2007).Since DEHP is not permanently bound to the PVC polymer in
Di(2-ethylhexyl) phthalate (DEHP) is a common indoor pollutant in the world which may cause lots of harmful effects in human including diabetes according to epidemiological studies. To explore the underlying role of DEHP in diabetes-like symptoms Balb/c mice were chose to be the experimental animals in this paper. They were separated as eight groups as follows (1) saline normal diet
2019-1-18 · phthalates DEHP DBP DiBP and BBP as toxic to reproductive health for example. In ani-mal trials Di(2-propylheptyl) phthalate (DPHP) has a harmful effect on the pituitary gland (hypophysis) and on the vital endocrine hormone the thyroid. The pituitary gland controls important bodily functions and the hormonal system of the body.
2018-2-22 · Di-2-ethylhexyl phthalate (DEHP) is extensively used as a plasticizer in many products especially medical devices furniture materials cosmetics and personal care products. DEHP is noncovalently bound to plastics and therefore it will leach out of these products after repeated use heating and/or cleaning of the products.
2019-8-1 · As one of the most common PAEs di-2-ethylhexyl phthalate (DEHP) has been shown by toxicological studies to be an endocrine disruptor that may cause cancer in humans and is listed as a priority contaminant by the US Environmental Protection Agency (USEPA) (Martino-Andrade and Chahoud 2010 Gao et al. 2016a Chen et al. 2018).
2004-9-1 · Di(2-ethylhexyl) phthalate (DEHP) is used to make polyvinyl chloride (PVC) plastic tubing soft and flexible. Animal data show that adverse effects of DEHP exposure may include reduced fertility reduced sperm production in males and ovarian dysfunction in females.
2021-7-22 · The human population may be exposed to DEHP by swallowing it for example in food by breathing it in and to a much lesser extent by skin contact. Risks are assessed by dividing worst-case exposures to the exposures at which no harmful effects were observed in animal studies. This gives the margin of safety (MOS).
2013-12-5 · Di-2-ethylhexyl phthalate (DEHP) is a reproductive and developmental toxicant and the developing male reproductive tract is most sensitive to DEHP exposures. Because DEHP is used in many consumer products and is a ubiquitous environmental contami-nant humans are exposed to DEHP at some level on a daily basis throughout life from conception
California ResidentsProposition 65. WARNING This product can expose you to chemicals including Di (2-ethylhexyl) phthalate (DEHP) which is known to the state of California to cause cancer and birth defects or other reproductive harm. For more information go to P65WArnings.ca.gov.
2011-10-6 · Approximately 55 of ingested DEHP is absorbed. DEHP is poorly absorbed through the skin. There are no quantitative absorption data for the inhalation route. Following ingestion DEHP is rapidly broken down in the gut to mono(2-ethylhexyl)phthalate and 2-ethylhexanol. 3 DEHP is lipophilic and tends to accumulate in adipose tissues.
2018-4-16 · Di‐(2‐ethylhexyl) phthalate (DEHP) is an environmental endocrine disruptor widely used in China that is harmful to the male reproductive system. Many studies have shown that DEHP causes testicular toxicity through oxidative stress but the specific mechanism is unknown. Because the Notch pathway is a key mechanism for regulating cell growth
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